EXHIBIT ID: LU_A_1004

Mechanism of Pulmonary Embolism in an Obese Male

This 3d custom medical animation focuses on an embolus formation. A lower leg vein is shown in a cross sectional view showing how valves prevent backflow of blood as it is returned to the heart. DVT, Deep Vein Thrombosis formation occurs, breaks off travels through the bloodstream up to the heart. A saddle embolus causes sudden fatal blockage of blood flow in the pulmonary artery. No flow can get to the lungs.