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EXHIBIT ID: EN_C_0115

Progression of Esophageal Perforation

Progression of Esophageal Perforation

The cross-sectional view of an esophageal perforation progression. The initial condition shows the layers of the esophageal wall including the muscularis propria, submucosa, mucosa, and the adventitia with a slight abrasion. The subsequent condition shows esophageal swelling with later onset of necrosis. The eventful condition displays perforation of the esophagus.